CHARACTERIZATION OF PELLICLE INHIBITION IN GLUCONACETOBACTER XYLINUS 53582 BY A SMALL MOLECULE, PELLICIN, IDENTIFIED BY A CHEMICAL GENETICS SCREEN.

Characterization of pellicle inhibition in Gluconacetobacter xylinus 53582 by a small molecule, pellicin, identified by a chemical genetics screen.

Pellicin ([2E]-3-phenyl-1-[2,3,4,5-tetrahydro-1,6-benzodioxocin-8-yl]prop-2-en-1-one) was identified in a chemical genetics screen of 10,000 small molecules for its ability to completely abolish pellicle production in Gluconacetobacter xylinus.Cells grown in the presence of pellicin grew 1.5 times faster than untreated cells.Interestingly, growth i

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